Table of Contents
ISRN Obstetrics and Gynecology
Volume 2013 (2013), Article ID 269425, 4 pages
http://dx.doi.org/10.1155/2013/269425
Clinical Study

The Importance of Gestational Sac Size of Ectopic Pregnancy in Response to Single-Dose Methotrexate

1Department of Obstetrics and Gynecology, Mahdiyeh Hospital, Shahid Beheshti University of Medical Sciences, No. 16, Fadaieaneslam Street, Shoush Avenue, Tehran 1185817311, Iran
2Department of Obstetrics and Gynecology, Tehran University of Medical Sciences, Tehran 1417614411, Iran

Received 17 December 2012; Accepted 5 February 2013

Academic Editors: L. G. Bahamondes, J. A. Cesar, and I. Diez-Itza

Copyright © 2013 Parichehr Kimiaei et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. Lau and T. Tulandi, “Conservative medical and surgical management of interstitial ectopic pregnancy,” Fertility & Sterility, vol. 72, no. 2, pp. 207–215, 1999. View at Publisher · View at Google Scholar · View at Scopus
  2. D. Mureşan, F. Stamatian, D. Ona et al., “Current trends in the treatment of ectopic pregnancy,” Chirurgia, vol. 103, no. 1, pp. 73–78, 2008. View at Google Scholar · View at Scopus
  3. P. Toozs-Hobson, J. Bidmead, A. Khalid, L. Cardozo, and S. Hill, “Current trends in management of ectopic pregnancy in the United Kingdom,” Journal of Obstetrics and Gynaecology, vol. 20, no. 1, pp. 74–77, 2000. View at Google Scholar · View at Scopus
  4. B. Pekhlivanov and N. Milchev, “Conservative treatment of ectopic pregnancy with methotrexate,” Akusherstvo i Ginekologiia, vol. 41, no. 6, pp. 53–56, 2002. View at Google Scholar · View at Scopus
  5. H. Fernandez, S. C. A. Y. Vincent, S. Pauthier, F. Audibert, and R. Frydman, “Randomized trial of conservative laparoscopic treatment and methotrexate administration in ectopic pregnancy and subsequent fertility,” Human Reproduction, vol. 13, no. 11, pp. 3239–3243, 1998. View at Google Scholar · View at Scopus
  6. G. H. Lipscomb, M. L. McCord, T. G. Stovall, G. Huff, S. G. Portera, and F. W. Ling, “Predictors of success of methotrexate treatment in women with tubal ectopic pregnancies,” The New England Journal of Medicine, vol. 341, no. 26, pp. 1974–1978, 1999. View at Publisher · View at Google Scholar · View at Scopus
  7. B. W. Mol, P. J. Hajenius, and F. van der Veen, “Predictors of success of methotrexate treatment in women with tubal ectopic pregnancies,” The New England Journal of Medicine, vol. 342, no. 15, p. 1138, 2000. View at Publisher · View at Google Scholar · View at Scopus
  8. C. S. Stika, L. Anderson, and M. C. Frederiksen, “Single-dose methotrexate for the treatment of ectopic pregnancy: Northwestern Memorial Hospital three-year experience,” American Journal of Obstetrics and Gynecology, vol. 174, no. 6, pp. 1840–1848, 1996. View at Publisher · View at Google Scholar · View at Scopus
  9. A. E. French and G. Koren, “Motherisk update: effect to methotrexate on male fertility,” Canadian Family Physician, vol. 49, pp. 577–578, 2003. View at Google Scholar · View at Scopus
  10. M. Feldkamp and J. C. Carey, “Clinical teratology counseling and consultation case report: low dose methotrexate exposure in the early weaks of pregnancy,” Teratology, vol. 47, no. 6, pp. 533–539, 1993. View at Google Scholar · View at Scopus
  11. M. E. Lloyd, M. Carr, P. McElhatton, G. M. Hall, and R. A. Hughes, “The effects of methotrexate on pregnancy, fertility and lactation,” QJM, vol. 92, no. 10, pp. 551–563, 1999. View at Google Scholar · View at Scopus
  12. A. Tawfiq, A. F. Agameya, and P. Claman, “Predictors of treatment failure for ectopic pregnancy treated with single-dose methotrexate,” Fertility & Sterility, vol. 74, no. 5, pp. 877–880, 2000. View at Publisher · View at Google Scholar · View at Scopus
  13. M. Erdem, A. Erdem, M. Arslan, A. Oç, K. Biberoǧlu, and R. Gürsoy, “Single-dose methotrexate for the treatment of unruptured ectopic pregnancy,” Archives of Gynecology and Obstetrics, vol. 270, no. 4, pp. 201–204, 2004. View at Google Scholar · View at Scopus
  14. P. G. Conaghan and P. Brooks, “Disease-modifying antirheumatic drugs, including methotrexate, gold, sulfasalazine, antimalarials, and D-penicillamine,” Current Opinion in Rheumatology, vol. 8, no. 3, pp. 176–182, 1996. View at Google Scholar · View at Scopus
  15. T. G. Stovall, F. W. Ling, and L. A. Gray, “Single-dose methotrexate for treatment of ectopic pregnancy,” Obstetrics and Gynecology, vol. 77, no. 5, pp. 754–757, 1991. View at Google Scholar · View at Scopus
  16. G. H. Corsan, M. Karacan, S. Qasim, M. K. Bohrer, M. X. Ransom, and E. Kemmann, “Identification of hormonal parameters for successful systemic single-dose methotrexate therapy in ectopic pregnancy,” Human Reproduction, vol. 10, no. 10, pp. 2719–2722, 1995. View at Google Scholar · View at Scopus
  17. M. B. Potter, L. A. Lepine, and D. J. Jamieson, “Predictors of success with methotrexate treatment of tubal ectopic pregnancy at Grady Memorial Hospital,” American Journal of Obstetrics and Gynecology, vol. 188, no. 5, pp. 1192–1194, 2003. View at Publisher · View at Google Scholar · View at Scopus
  18. J. L. Glock, J. V. Johnson, and J. R. Brumsted, “Efficacy and safety of single-dose systemic methotrexate in the treatment of ectopic pregnancy,” Fertility & Sterility, vol. 62, no. 4, pp. 716–721, 1994. View at Google Scholar · View at Scopus
  19. G. H. Lipscomb, D. Bran, M. L. McCord et al., “Analysis of three hundred fifteen ectopic pregnancies treated with single-dose methotrexate,” American Journal of Obstetrics and Gynecology, vol. 178, no. 6, pp. 1354–1358, 1998. View at Publisher · View at Google Scholar · View at Scopus
  20. T. G. Stovall and F. W. Ling, “Single-dose methotrexate: an expanded clinical trial,” American Journal of Obstetrics and Gynecology, vol. 168, no. 6, pp. 1759–1765, 1993. View at Google Scholar · View at Scopus
  21. A. Alleyassin, A. Khademi, M. Aghahosseini, L. Safdarian, B. Badenoosh, and E. A. Hamed, “Comparison of success rates in the medical management of ectopic pregnancy with single-dose and multiple-dose administration of methotrexate: a prospective, randomized clinical trial,” Fertility & Sterility, vol. 85, no. 6, pp. 1661–1666, 2006. View at Publisher · View at Google Scholar · View at Scopus