Patient with Large Colloid Drusen in both eyes. (a), (c) Color fundus photographs show large drusen in the macular area and in the periphery of the retina. (b), (d) SD-OCT shows hyperreflective deposits located above the RPE (white arrows). An abrupt interruption of both the inner band of RPE and IS/OS interface appears at the border of these hyperreflective lesions. Hyporeflective cysts are observed in the inner retina along with an epiretinal membrane (black arrow).