Table of Contents
ISRN Nephrology
Volume 2013 (2013), Article ID 280395, 6 pages
http://dx.doi.org/10.5402/2013/280395
Research Article

Vitamin E Is a Nephroprotectant Agent in Male but Not in Female in a Model of Cisplatin-Induced Nephrotoxicity

1Water & Electrolytes Research Center, Isfahan University of Medical Sciences, Isfahan 81745, Iran
2Deparment of Biology, Falavarjan Branch, Islamic Azad University, Isfahan 84515, Iran
3Department of Physiology, Isfahan University of Medical Sciences, Isfahan 81745, Iran
4Kidney Diseases Research Center, Isfahan University of Medical Sciences, Isfahan 81745, Iran
5Department of Clinical Pathology, Isfahan University of Medical Sciences, Isfahan 81745, Iran
6Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan 81745, Iran

Received 14 May 2013; Accepted 9 June 2013

Academic Editors: B. Di Iorio, E. F. Elsayed, C. Fourtounas, and G. Gonlusen

Copyright © 2013 Sima Jilanchi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. Dalla Via, V. Di Noto, M. Vidali, F. Scomazzon, D. Ni, and R. Deana, “Action of antitumoral platinum complexes on in vitro platelet functions,” Chemico-Biological Interactions, vol. 110, no. 3, pp. 203–220, 1998. View at Publisher · View at Google Scholar · View at Scopus
  2. J. Liu, Y. Liu, S. S. M. Habeebu, and C. D. Klaassen, “Metallothionein (MT)-null mice are sensitive to cisplatin-induced hepatotoxicity,” Toxicology and Applied Pharmacology, vol. 149, no. 1, pp. 24–31, 1998. View at Publisher · View at Google Scholar · View at Scopus
  3. B. Rosenberg, “Charles F. Kettring prize. Fundamental studies with cisplatin,” Cancer, vol. 55, no. 10, pp. 2303–2316, 1985. View at Google Scholar · View at Scopus
  4. R. Baliga, Z. Zhang, M. Baliga, N. Ueda, and S. V. Shah, “In vitro and in vivo evidence suggesting a role for iron in cisplatin-induced nephrotoxicity,” Kidney International, vol. 53, no. 2, pp. 394–401, 1998. View at Publisher · View at Google Scholar · View at Scopus
  5. H. Matsushima, K. Yonemura, K. Ohishi, and A. Hishida, “The role of oxygen free radicals in cisplatin-induced acute renal failure in rats,” Journal of Laboratory and Clinical Medicine, vol. 131, no. 6, pp. 518–526, 1998. View at Google Scholar · View at Scopus
  6. Y. Sadzuka, T. Shoji, and Y. Takino, “Mechanism of the increase in lipid peroxide induced by cisplatin in the kidneys of rats,” Toxicology Letters, vol. 62, no. 2-3, pp. 293–300, 1992. View at Publisher · View at Google Scholar · View at Scopus
  7. S. Kohn, M. Fradis, L. Podoshin, J. Ben-David, J. Zidan, and E. Robinson, “Endothelial injury of capillaries in the stria vascularis of guinea pigs treated with cisplatin and gentamicin,” Ultrastructural Pathology, vol. 21, no. 3, pp. 289–299, 1997. View at Google Scholar · View at Scopus
  8. H. Ito, T. Okafuji, and T. Suzuki, “Vitamin E prevents endothelial injury associated with cisplatin injection into the superior mesenteric artery of rats,” Heart and Vessels, vol. 10, no. 4, pp. 178–184, 1995. View at Publisher · View at Google Scholar · View at Scopus
  9. J.-G. Zhang and W. E. Lindup, “Role of mitochondria in cisplatin-induced oxidative damage exhibited by rat renal cortical slices,” Biochemical Pharmacology, vol. 45, no. 11, pp. 2215–2222, 1993. View at Publisher · View at Google Scholar · View at Scopus
  10. J. A. Gordon and V. H. Gattone II, “Mitochondrial alterations in cisplatin-induced acute renal failure,” The American Journal of Physiology, vol. 250, no. 6, pp. F991–F998, 1986. View at Google Scholar · View at Scopus
  11. P. M. Macleod, C. J. Tyrell, and D. H. Keeling, “The effect of cisplatin on renal function in patients with testicular tumours,” Clinical Radiology, vol. 39, no. 2, pp. 190–192, 1988. View at Google Scholar · View at Scopus
  12. G. Daugaard, U. Abildgaard, N. H. Holstein-Rathlou, P. Leyssac, O. Amtorp, and T. Dikhoff, “Acute effect of cisplatin on renal hemodynamics and tubular function in dog kidneys,” Kidney and Blood Pressure Research, vol. 9, no. 5, pp. 308–316, 1986. View at Google Scholar
  13. S. Saleh and E. El-Demerdash, “Protective effects of L-arginine against cisplatin-induced renal oxidative stress and toxicity: role of nitric oxide,” Basic and Clinical Pharmacology and Toxicology, vol. 97, no. 2, pp. 91–97, 2005. View at Google Scholar
  14. D. Appenroth, S. Fröb, L. Kersten, F.-K. Splinter, and K. Winnefeld, “Protective effects of vitamin E and C on cisplatin nephrotoxicity in developing rats,” Archives of Toxicology, vol. 71, no. 11, pp. 677–683, 1997. View at Publisher · View at Google Scholar · View at Scopus
  15. X. Wang and P. J. Quinn, “Vitamin E and its function in membranes,” Progress in Lipid Research, vol. 38, no. 4, pp. 309–336, 1999. View at Publisher · View at Google Scholar · View at Scopus
  16. M. NazÄroÇlu, A. KaraoÄŸlu, and A. O. Aksoy, “Selenium and high dose vitamin E administration protects cisplatin-induced oxidative damage to renal, liver and lens tissues in rats,” Toxicology, vol. 195, no. 2, pp. 221–230, 2004. View at Google Scholar
  17. S. Atasayar, H. Gürer-Orhan, H. Orhan, B. Gürel, G. Girgin, and H. Özgüneş, “Preventive effect of aminoguanidine compared to vitamin E and C on cisplatin-induced nephrotoxicity in rats,” Experimental and Toxicologic Pathology, vol. 61, no. 1, pp. 23–32, 2009. View at Publisher · View at Google Scholar · View at Scopus
  18. M. Nematbakhsh, F. Ashrafi, T. Safari, A. Talebi, H. Nasri, M. Mortazavi et al., “Administration of vitamin E and losartan as prophylaxes in cisplatin-induced nephrotoxicity model in rats,” Journal of Nephrology, vol. 25, no. 3, pp. 410–417, 2012. View at Google Scholar
  19. Y. O. Ilbey, E. Ozbek, M. Cekmen, A. Simsek, A. Otunctemur, and A. Somay, “Protective effect of curcumin in cisplatin-induced oxidative injury in rat testis: mitogen-activated protein kinase and nuclear factor-kappa B signaling pathways,” Human Reproduction, vol. 24, no. 7, pp. 1717–1725, 2009. View at Publisher · View at Google Scholar · View at Scopus
  20. Q. He, C. H. Liang, and S. J. Lippard, “Steroid hormones induce HMG1 overexpression and sensitize breast cancer cells to cisplatin and carboplatin,” Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 11, pp. 5768–5772, 2000. View at Publisher · View at Google Scholar · View at Scopus
  21. F. Eshraghi-Jazi, M. Nematbakhsh, H. Nasri et al., “The protective role of endogenous nitric oxide donor (L-arginine) in cisplatin-induced nephrotoxicity: gender related differences in rat model,” Journal of Research in Medical Sciences, vol. 16, no. 11, pp. 1389–1396, 2011. View at Google Scholar · View at Scopus
  22. M. Haghighi, M. Nematbakhsh, A. Talebi, H. Nasri, F. Ashrafi, K. Roshanaei et al., “The role of angiotensin II receptor 1 (AT1) blockade in cisplatin-induced nephrotoxicity in rats: gender-related differences,” Renal Failure, vol. 34, no. 8, pp. 1046–1051, 2012. View at Google Scholar
  23. M. Nematbakhsh, Z. Pezeshki, F. Eshraghi-Jazi, F. Ashrafi, H. Nasri, A. Talebi et al., “Vitamin E, Vitamin C, or Losartan is not nephroprotectant against cisplatin-induced nephrotoxicity in presence of estrogen in ovariectomized rat model,” International Journal of Nephrology, vol. 2012, Article ID 284896, 2012. View at Google Scholar
  24. D. Stakisiaitis, G. Dude-niene, R. J. Jankunas, G. Grazeliene, J. Didziapetriene, and B. Pundziene, “Cisplatin increases urinary sodium excretion in rats: gender-related differences,” Medicina, vol. 46, no. 1, pp. 45–50.
  25. Q. Wei, M.-H. Wang, and Z. Dong, “Differential gender differences in ischemic and nephrotoxic acute renal failure,” The American Journal of Nephrology, vol. 25, no. 5, pp. 491–499, 2005. View at Publisher · View at Google Scholar · View at Scopus
  26. U. Ammer, Y. Natochin, C. David, G. Rumrich, and K. J. Ullrich, “Cisplatin nephrotoxicity: site of functional disturbance and correlation to loss of body weight,” Renal Physiology and Biochemistry, vol. 16, no. 3, pp. 131–145, 1993. View at Google Scholar · View at Scopus
  27. H. I. El-Sayyad, M. F. Ismail, F. M. Shalaby et al., “Histopathological effects of cisplatin, doxorubicin and 5-flurouracil (5-FU) on the liver of male albino rats,” International Journal of Biological Sciences, vol. 5, no. 5, pp. 466–473, 2009. View at Google Scholar · View at Scopus
  28. T. Ohno, S. Kato, M. Wakatsuki et al., “Incidence and temporal pattern of anorexia, diarrhea, weight loss, and leukopenia in patients with cervical cancer treated with concurrent radiation therapy and weekly cisplatin: comparison with radiation therapy alone,” Gynecologic Oncology, vol. 103, no. 1, pp. 94–99, 2006. View at Publisher · View at Google Scholar · View at Scopus
  29. K. V. Kumar, A. A. Shifow, M. U. R. Naidu, and K. S. Ratnakar, “Carvedilol: a beta blocker with antioxidant property protects against gentamicin-induced nephrotoxicity in rats,” Life Sciences, vol. 66, no. 26, pp. 2603–2611, 2000. View at Google Scholar · View at Scopus
  30. S. K. Jain and M. Palmer, “The effect of oxygen radicals metabolites and vitamin E on glycosylation of proteins,” Free Radical Biology and Medicine, vol. 22, no. 4, pp. 593–596, 1997. View at Publisher · View at Google Scholar · View at Scopus
  31. V. Mavichak, N. L. M. Wong, and G. A. Quamme, “Studies on the pathogenesis of cisplatin-induced hypomagnesemia in rats,” Kidney International, vol. 28, no. 6, pp. 914–921, 1985. View at Google Scholar · View at Scopus
  32. M. Khazaei, P. Bayat, A. Ghanbari, S. Khazaei, M. Feizian, A. Khodaei et al., “Protective effects of subchronic caffeine administration on cisplatin induced urogenital toxicity in male mice,” Indian Journal of Experimental Biology, vol. 50, pp. 638–644, 2012. View at Google Scholar
  33. H. Luo, S. Ge, D. Yue, L. Yan, X. Xu, K. Liu et al., Effect of Vitamin E on the Development of Testis in Sheep, 2011.
  34. Y. Harima, K. Harima, T. Hasegawa, N. Shikata, and Y. Tanaka, “Histopathological changes in rabbit uterus carcinoma alter transcatheter arterial embolization using cisplatin,” Cancer Chemotherapy and Pharmacology, vol. 38, no. 4, pp. 317–322, 1996. View at Publisher · View at Google Scholar · View at Scopus
  35. F. Maneschi, P. Benedetti-Panici, G. Scambia, M. G. Salerno, G. D'Agostino, and S. Mancuso, “Menstrual and hormone patterns in women treated with high-dose cisplatin and bleomycin,” Gynecologic Oncology, vol. 54, no. 3, pp. 345–348, 1994. View at Publisher · View at Google Scholar · View at Scopus
  36. G. M. Rubanyi, A. D. Freay, K. Kauser et al., “Vascular estrogen receptors and endothelium-derived nitric oxide production in the mouse aorta: gender difference and effect of estrogen receptor gene disruption,” Journal of Clinical Investigation, vol. 99, no. 10, pp. 2429–2437, 1997. View at Google Scholar · View at Scopus
  37. U. C. Garg and A. Hassid, “Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells,” Journal of Clinical Investigation, vol. 83, no. 5, pp. 1774–1777, 1989. View at Google Scholar · View at Scopus
  38. K.-I. Watanabe, A. Hess, W. Bloch, and O. Michel, “Expression of inducible nitric oxide synthase (iNOS/NOS II) in the vestibule of guinea pigs after the application of cisplatin,” Anti-Cancer Drugs, vol. 11, no. 1, pp. 29–32, 2000. View at Publisher · View at Google Scholar · View at Scopus
  39. R. C. Srivastava, A. Farookh, N. Ahmad, M. Misra, S. K. Hasan, and M. M. Husain, “Evidence for the involvement of nitric oxide in cisplatin-induced toxicity in rats,” BioMetals, vol. 9, no. 2, pp. 139–142, 1996. View at Google Scholar · View at Scopus
  40. M. A. Beleh, Y. C. Lin, and R. W. Brueggemeier, “Estrogen metabolism in microsomal, cell, and tissue preparations of kidney and liver from Syrian hamsters,” Journal of Steroid Biochemistry and Molecular Biology, vol. 52, no. 5, pp. 479–489, 1995. View at Publisher · View at Google Scholar · View at Scopus