International Scholarly Research Notices / 2013 / Article / Tab 3 / Review Article
Platinum and Palladium Polyamine Complexes as Anticancer Agents: The Structural Factor Table 3 Vibrational spectroscopy studies (coupled to theoretical calculations) on platinum and palladium complexes with amine ligands, developed as anticancer agents.
Compound
g TechniqueWork Cisplatin DFT calc. [260 ] Cisplatin DFT/ECP calc. [261 ] Cisplatin DFT/ECP calc. [339 ] Cisplatin DFT/ECP calc. [340 ] Cisplatin, carboplatin DFT/ECP calc [341 ] Cisplatin, carboplatin DFT/ECP, PW calc [305 ] Carboplatin DFT/ECP calc [344 ] Pt(II)-diaminopropane DFT/ECP calc [181 ] cis -Pt(II)-diamine-orotatoDFT/ECP calc [346 ]
a Pd3 Spd2 AFM [178 ]
b Pd2 SpmAFM [178 ]
c Pt3 (NSpd2 )Cl6 Raman, FTIR [77 ]
d Pt2 (CPENSpm)Cl4 Raman, FTIR [77 ] Pd3 (NSpd2 )Cl6 Raman, FTIR [77 ]
e Pd2 (BENSpm)Cl4 Raman, FTIR [77 ] Cisplatin-nucleotide adducts Resonance Raman [306 ] Cisplatin-DNA adducts Raman [309 ] Cisplatin-DNA adducts SERS [310 ] Cisplatin-guanine adducts DFT/ECP calc [307 , 308 ] Carboplatin-guanine adducts Raman, SERS [307 ] Carboplatin-nucleotide adducts Resonance Raman [306 ]
f Oxaliplatin-HSA interactionFTIR [312 ] Pd3 Spd2 -DNA adducts AFM [179 ] Pd2 Spm-DNA adducts AFM [179 ] Cisplatin-membrane interaction Pressure tuning FTIR [313 ] Cisplatin actin FT-Raman [311 ] Nanotube-encapsulated cisplatin MicroRaman [356 ] Response to cisplatin in leukemia MicroRaman [357 ] Response to cisplatin in gastric cancer Raman [358 ] Response to cisplatin in lung cancer MicroRaman [333 , 335 ]
a Spd: spermidine. b Spm: spermine. c NSpd: norspermidine, H2 N(CH2 )3 NH(CH2 )3 NH2 . d CPENSpm: N1 -cyclopropyl-methyl-N11 -ethylnorspermine, (CH2 C3 H5 )HN(CH2 )3 NH(CH2 )3 NH(CH2 )3 NH(CH3 CH2 ). e BENSpm: N1 ,N11 -bis (ethyl)norspermine, (CH3 CH2 )HN(CH2 )3 NH(CH2 )3 NH(CH2 )3 NH(CH3 CH2 ). f HSA: human serum albumin. g DFT: density functional theory; ECP: effective core potentials; PW: plane wave; FTIR: Fourier transform infrared spectroscopy; INS: inelastic neutron scattering spectroscopy; FT-Raman: Fourier transform Raman spectroscopy; SERS: surface enhanced Raman spectroscopy; AFM: atomic force microscopy.
