Clinical Study

Colon Mucosa Exhibits Loss of Ectopic MUC5AC Expression in Patients with Ulcerative Colitis Treated with Oral Tacrolimus

Table 1

Patients' baseline characteristics (n = 26).

Sex (male/female)12/14
Age at diagnosis
median (range) (years)
37.4 (16–78)
Age at start of the therapy
median (range) (years)
43.6 (17–81)
Disease duration
median (range) (years)
6.1 (0.5–21)
Extent of disease
 Extensive (%)16 (61.5%)
 Left sided (%)10 (38.5%)
Response to corticosteroids
 Steroid resistance (%)3 (11.5%)
 Steroid dependent (%)23 (88.5%)
Concomitant medication
 Predonisolone (≥10 mg/day)19
 5-Aminosalicylates23
Immunosuppressants (AZA or 6-MP)4
 Infliximab1
 GMA23

AZA: azathioprine; 6-MP: 6-mercaptopurine; GMA: granulocyte and monocyte adsorptive apheresis.