Clinical Study
Colon Mucosa Exhibits Loss of Ectopic MUC5AC Expression in Patients with Ulcerative Colitis Treated with Oral Tacrolimus
Table 1
Patients' baseline characteristics (n = 26).
| Sex (male/female) | 12/14 | Age at diagnosis median (range) (years) | 37.4 (16–78) | Age at start of the therapy median (range) (years) | 43.6 (17–81) | Disease duration median (range) (years) | 6.1 (0.5–21) | Extent of disease | | Extensive (%) | 16 (61.5%) | Left sided (%) | 10 (38.5%) | Response to corticosteroids | | Steroid resistance (%) | 3 (11.5%) | Steroid dependent (%) | 23 (88.5%) | Concomitant medication | | Predonisolone (≥10 mg/day) | 19 | 5-Aminosalicylates | 23 | Immunosuppressants (AZA or 6-MP) | 4 | Infliximab | 1 | GMA | 23 |
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AZA: azathioprine; 6-MP: 6-mercaptopurine; GMA: granulocyte and monocyte adsorptive apheresis.
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