Obesity and African Americans: Physiologic and Behavioral Pathways
Table 3
Plasma glucose and insulin concentrations, calculated HOMA, and glucose and insulin AUC following a meal under placebo and dexamethasone conditions by African Americans () and Caucasian Americans (); (mean ± SD).
Placebo
Dexamethasone
African Americans
Caucasians
African Americans
Caucasians
Glucose (mmol/L)
5.3 ± 0.6
5.6 ± 0.8
6.4 ± 0.8
7.0 ± 1.2**
Insulin (μIU/mL)
15 ± 11.8
11 ± 08.2**
22 ± 15.0
15 ± 09.2**
HOMA
3.7 ± 3.0
2.7 ± 2.3*
6.6 ± 05.1
4.8 ± 3.0*
Postprandial insulin AUC
7874 ± 4801
4510 ± 2878**
13715 ± 9544
7237 ± 4658**
Postprandial glucose AUC
32.0 ± 47.0
44.0 ± 49.0
72.0 ± 76
94 ± 85
Peak postprandial insulin
186 ± 127.0
107 ± 69.4**
337 ± 278
175 ± 113.7**
Homeostasis model assessment (HOMA); area under curve (AUC). Note: *P < 0.05; **P < 0.01; P values represent comparisons between African Americans and Caucasians, and not treatment conditions. From [18].
