International Scholarly Research Notices / 2013 / Article / Tab 7

Review Article

Glomerular Disease in Patients with Infectious Processes Developing Antineutrophil Cytoplasmic Antibodies

Table 7

Treatment and outcomes of 50 patients with development of ANCA positivity and glomerulonephritis during the course of infectious episodes.

Treatment method (%)Outcome (%)

Pauci-immune glomerulonephritis123
 Antibiotics10 (43)Improvement/recovery17 (74)
 Corticosteroids22 (96)Death3 (13)
 Cyclophosphamide17 (74)Not reported3 (13)
 Plasma exchange2 (9)
 Interferon-a2b1 (4)
 Aortic valve replacement1 (4)
Postinfectious glomerulonephritis119
 Antibiotics17 (89)Improvement/recovery14 (74)
 Corticosteroids11 (58)Dialysis3 (16)
 Cardiac valve replacement 3 (16)Death5 (26)
 Atrioventricular shunt removal3 (16)
 Ventricular septal defect repair1 (5)
 Intravenous immunoglobulins1 (5)
 Plasma exchange1 (5)
 Interferon-a2b1 (5)
 Cyclophosphamide 1 (5)
Other types of renal disease9
 Antibiotics8 (89)Improvement/recovery6 (67)
 Corticosteroids2 (22)Chronic renal failure2 (22)
 Aortic valve replacement1 (11)Death1 (11)
 Cyclophosphamide1 (11)

1Including two patients with dual glomerulopathy [120, (a) and (b)].