Table of Contents
ISRN Chromatography
Volume 2013 (2013), Article ID 328157, 8 pages
http://dx.doi.org/10.1155/2013/328157
Research Article

Cefpodoxime Proxetil: A New Stability Indicating RP-HPLC Method

1Gokaraju Rangaraju College of Pharmacy, Osmania University, Bachupally, Hyderabad 500 090, India
2Jawaharlal Nehru Technological University, Hyderabad 500 085, India

Received 24 April 2013; Accepted 29 May 2013

Academic Editors: J. A. P. Coelho, B. Fernandez De Simon, and M. Hassan

Copyright © 2013 Ceema Mathew et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Guidelines for Submitting Documentation for the Stability of Human Drugs and Biologics, Food and Drug Administration, Rockvillae, Md, USA, 1987.
  2. “Stability testing of new drug substances and products Q1A,” in Proceedings of the International Conference on Harmonization, Geneva, Switzerland, 1993.
  3. M. Bakshi and S. Singh, “Development of validated stability-indicating assay methods—critical review,” Journal of Pharmaceutical and Biomedical Analysis, vol. 28, no. 6, pp. 1011–1040, 2002. View at Publisher · View at Google Scholar · View at Scopus
  4. J. T. Carstensen and C. T. Rhodes, “Development and validation of HPLC stability indicating assays,” in Drug Stability—Principles and Practices, p. 331, Marcel Dekker, New York, NY, USA, 3rd edition, 2005. View at Google Scholar
  5. M. T. Borin, “A review of the pharmacokinetics of cefpodoxime proxetil,” Drugs, vol. 42, supplement 3, pp. 13–21, 1991. View at Google Scholar · View at Scopus
  6. E. Bergogne-Berezin, “Cefpodoxime in upper respiratory tract infections,” Drugs, vol. 42, no. 3, pp. 25–33, 1991. View at Google Scholar · View at Scopus
  7. A. M. Geddes, “Cefpodoxime proxetil in the treatment of lower respiratory tract infections,” Drugs, vol. 42, supplement 3, pp. 34–40, 1991. View at Google Scholar · View at Scopus
  8. V. K. Kakumanu, V. Arora, and A. K. Bansal, “Investigation on physicochemical and biological differences of cefpodoxime proxetil enantiomers,” European Journal of Pharmaceutics and Biopharmaceutics, vol. 64, no. 2, pp. 255–259, 2006. View at Publisher · View at Google Scholar · View at Scopus
  9. E. C. Chocas, C. M. Paap, and P. J. Godley, “Cefpodoxime proxetil: a new, broad-spectrum, oral cephalosporin,” Annals of Pharmacotherapy, vol. 27, no. 11, pp. 1369–1377, 1993. View at Google Scholar · View at Scopus
  10. F. Camus, A. Deslandes, L. Harcouet, and R. Farinotti, “High-performance liquid chromatographic method for the determination of cefpodoxime levels in plasma and sinus mucosa,” Journal of Chromatography B, vol. 656, no. 2, pp. 383–388, 1994. View at Publisher · View at Google Scholar · View at Scopus
  11. V. K. Kakumanu, V. K. Arora, and A. K. Bansal, “Development and validation of isomer specific RP-HPLC method for quantification of cefpodoxime proxetil,” Journal of Chromatography B, vol. 835, no. 1-2, pp. 16–20, 2006. View at Publisher · View at Google Scholar · View at Scopus
  12. M. J. Lovdahl, K. E. Reher, H. Q. Russlie, and D. M. Canafax, “Determination of cefpodoxime levels in chinchilla middle ear fluid and plasma by high-performance liquid chromatography,” Journal of Chromatography B, vol. 653, no. 2, pp. 227–232, 1994. View at Publisher · View at Google Scholar · View at Scopus
  13. S. Malathi, R. N. Dubey, and R. Venkatnarayanan, “Simultaneous RP-HPLC estimation of cefpodoxime proxetil and clavulanic acid in tablets,” Indian Journal of Pharmaceutical Sciences, vol. 71, no. 1, pp. 102–105, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. F. Molina, F. Jehl, C. Gallion, F. Penner, and H. Monteil, “Determination of the third generation oral cephalosporin cefpodoxime in biological fluids by high-speed high-performance liquid chromatography,” Journal of Chromatography B, vol. 563, no. 1, pp. 205–210, 1991. View at Publisher · View at Google Scholar · View at Scopus
  15. G. Patel and S. Rajput, “Stress degradation studies on cefpodoxime proxetil and development of a validated stability-indicating HPLC method,” Acta Chromatographica, vol. 23, no. 2, pp. 215–234, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. N. Fukutsu, T. Kawasaki, K. Saito, and H. Nakazawa, “Application of high-performance liquid chromatography hyphenated techniques for identification of degradation products of cefpodoxime proxetil,” Journal of Chromatography A, vol. 1129, no. 2, pp. 153–159, 2006. View at Publisher · View at Google Scholar · View at Scopus
  17. K. Stoeckel, W. Hofheinz, J. P. Laneury, P. Duchene, S. Shedlofsky, and R. A. Blouin, “Stability of cephalosporin prodrug esters in human intestinal juice: implications for oral bioavailability,” Antimicrobial Agents and Chemotherapy, vol. 42, no. 10, pp. 2602–2606, 1998. View at Google Scholar · View at Scopus
  18. M.-J. Wang, W.-B. Zou, J. Xue, and C.-Q. Hu, “Comparison of three RP-HPLC methods for analysis of cefpodoxime proxetil and related substances,” Chromatographia, vol. 65, no. 1-2, pp. 69–75, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. P. Jain, A. Chaudhari, A. Bang, and S. Surana, “Validated stability-indicating high-performance thin-layer chromatographic method for estimation of cefpodoxime proxetil in bulk and in pharmaceutical formulation according to International conference on harmonization guidelines,” Journal of Pharmacy and Bioallied Sciences, vol. 4, no. 2, pp. 101–106, 2012. View at Publisher · View at Google Scholar · View at Scopus
  20. S. I. Bhoir, P. V. Gaikwad, L. S. Parab, R. N. Shringarpure, S. S. Savant, and P. J. Verma, “RP-HPLC method development and validation for the simultaneous estimation of satranidazole and ofloxacin in pharmaceutical dosage form,” Journal of Chromatographic Science, vol. 49, no. 1, pp. 84–87, 2011. View at Google Scholar · View at Scopus