Review Article

Nutrition, Inflammation, and Acute Pancreatitis

Table 1

Randomised controlled trials of total enteral versus total parenteral nutrition in patients with predicted severe acute pancreatitis.

Reference Year SettingPatients ( ) Allocation concealment Reduction of infectious complications and mortality
Enteral nutritionParenteral nutrition

Kalfarentzos et al. [70]1997Greece1820OpenlabelSignificantly lower rate of pancreatic infection in the total enteral nutrition group
Gupta et al. [43]2003UK89OpenlabelNon-significantly lower rate of pancreatic infection in the total enteral nutrition group
Louie et al. [71]2005Canada1018OpenlabelNon-significantly lower rate of pancreatic infection in the total enteral nutrition group
Eckerwall et al. [41]2006Sweden2325OpenlabelNo significant difference in outcomes
Petrov et al. [72]2006Russia3534OpenlabelSignificantly lower rate of pancreatic infection and mortality in the total enteral nutrition group
Casas et al. [73]2007Spain1111OpenlabelNon-significantly lower rate of pancreatic infection in the total enteral nutrition group
Doley et al. [74]2008India2525OpenlabelNo significant difference in the outcomes
Wu et al. [75]2010China5354OpenlabelSignificantly lower rate of pancreatic infection and mortality in the total enteral nutrition group