Table of Contents
ISRN Rheumatology
Volume 2013, Article ID 341832, 8 pages
Research Article

Effects of Low-Level Laser Therapy, 660 nm, in Experimental Septic Arthritis

1Laboratory of Injuries Study and Physical Therapy Resources of the State University of Western Paraná (UNIOESTE), Universitária Street, 2069 Jd. Universitário, P.O. Box 711, 85819-110 Cascavel, PR, Brazil
2UNIOESTE Pharmacy College, Brazil
3Laboratory of Cell Biology of the UNIOESTE, Brazil

Received 17 June 2013; Accepted 8 July 2013

Academic Editors: R. Marks and G. Murdaca

Copyright © 2013 Bruna Formentão Araujo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The effectiveness of low-level laser therapy (LLLT) in the presence of an infectious process has not been well elucidated. The aim of the study was to evaluate the effects of LLLT in an experimental model of septic arthritis. Methods. Twenty-one Wistar rats were divided as follows: control group, no bacteria; placebo group, bacteria were inoculated; Treated group, bacteria were injected and treatment with LLLTwas performed. To assess nociception, a von Frey digital analgesimeter was applied. Synovial fluid was streaked to analyze bacterial growth. The standard strain of S. aureus was inoculated in the right knee. LLLT was performed with 660 nm, 2 J/cm2, over 10 days. After treatment, the knees were fixed and processed for morphological analysis by light microscopy. Results. It was found that nociception increases in the right knee. There was a lack of results for the seeding of the synovial fluid. The morphological analysis showed slight recovery areas in the articular cartilage and synovia; however, there was the maintenance of the inflammatory infiltrate. Conclusion. The parameters used were not effective in the nociception reduction, even with the slight tissue recovery due to the maintenance of inflammatory infiltrate, but produced no change in the natural history of resolution of the infectious process.