Research Article

Screening of Most Effective Variables for Development of Gastroretentive Mucoadhesive Nanoparticles by Taguchi Design

Table 1

List of variables employed in Taguchi L8 orthogonal array experiment.

FactorsLevels
Low (−1)High (+1)

Amount of gelatin (mg)2001000
Amount of glutaraldehyde (mL)0.10.5
Amount of pluronic F-68 (mg)50250
Acetone addition rate (mL/min)15
pH24
Stirring time (h)15
Stirring speed (rpm)2001000