Screening of Most Effective Variables for Development of Gastroretentive Mucoadhesive Nanoparticles by Taguchi Design

Table 2

L8 array layout as per 7 factors, 2 levels Taguchi screening design.

Formulation code	Amount of gelatin (mg)	Amount of Glutaraldehyde (mL)	Amount of Pluronic F-68 (mg)	Acetone addition rate (mL/min)	pH	Stirring time (h)	Stirring speed (rpm)
F1	−1	−1	−1	−1	−1	−1	−1
F2	−1	+1	−1	+1	+1	+1	−1
F3	+1	+1	−1	−1	−1	+1	+1
F4	+1	−1	−1	+1	+1	−1	+1
F5	+1	−1	+1	+1	−1	+1	−1
F6	+1	+1	+1	−1	+1	−1	−1
F7	−1	+1	+1	+1	−1	−1	+1
F8	−1	−1	+1	−1	+1	+1	+1