International Scholarly Research Notices

Clinical Study

Similar Adverse Pregnancy Outcome in Native and Nonnative Dutch Women with Pregestational Type 2 Diabetes: A Multicentre Retrospective Study

General characteristics of the study population. values were calculated between the two ethnic groups.


Maternal characteristics	Native Dutch,	%	Nonnative Dutch,	%

Mean (SD) age in yrs					0.829
Mean (SD) body mass index in kg/m²					0.096
Median () GA at 1st booking in weeks	8.0 (6.0–10.3)		11.5 (8.0–19.0)		<0.001
Alcohol use	0	0	0	0	n/a
Smoking habits	11	13.8	11	5.7	0.06
Nulliparous	22	27.5	34	17.7	0.079
Median () duration of diabetes (yrs)	2.0 (1.0–5.8)		1.0 (0.0–3.0)		0.004
Chronic complications
Retinopathy	3	3.8	7	3.6	0.657
Neuropathy	1	1.3	2	1.0	0.65
Nephropathy	2	2.5	4	2.1	0.569
Cardiovascular	2	2.5	2	1.0	0.338
Preconceptional treatment of diabetes					<0.001
No	22	27.5	80	41.7
Oral	9	11.3	64	30.3
IIT	36	45.0	36	18.8
CSII	6	7.5	1	0.5
Unknown	7	8.8	11	5.7
Glycemic control
Median () HbA1c preconceptional	48 (39–59) ()*		52 (45–68) ()*		0.04
Median () HbA1c first trimester	45 (36–57) ()*		53 (43–66) ()*		0.001
Median () HbA1c second trimester	37 (34–43) ()*		45 (40–53) ()*		<0.001
Median () HbA1c third trimester	40 (34–44) ()*		42 (40–51) ()*		<0.001
Median () HbA1c during pregnancy	41 (36–48) ()*		48 (41–56) ()*		<0.001
Mean (SD) birth weight in grams					0.857

Number of available HbA1c samples.