Table of Contents
ISRN Allergy
Volume 2013, Article ID 361746, 10 pages
Review Article

Noneczematous Contact Dermatitis

Department of Biomedical Science and Human Oncology, Section of Dermatology, University of Bari, Piazza Giulio Cesare 1, 70124 Bari, Italy

Received 7 July 2013; Accepted 12 August 2013

Academic Editors: D. C. Cara, B. F. Gibbs, Y. L. Ye, and Z. Zhu

Copyright © 2013 Domenico Bonamonte et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Irritant or allergic contact dermatitis usually presents as an eczematous process, clinically characterized by erythematoedematovesicous lesions with intense itching in the acute phase. Such manifestations become erythematous-scaly as the condition progresses to the subacute phase and papular-hyperkeratotic in the chronic phase. Not infrequently, however, contact dermatitis presents with noneczematous features. The reasons underlying this clinical polymorphism lie in the different noxae and contact modalities, as well as in the individual susceptibility and the various targeted cutaneous structures. The most represented forms of non-eczematous contact dermatitis include the erythema multiforme-like, the purpuric, the lichenoid, and the pigmented kinds. These clinical entities must obviously be discerned from the corresponding “pure” dermatitis, which are not associated with contact with exogenous agents.