Comparative Effects of Phosphoenolpyruvate, a Glycolytic Intermediate, as an Organ Preservation Agent with Glucose and N-Acetylcysteine against Organ Damage during Cold Storage of Mouse Liver and Kidney

Figure 2

Changes in oxidative stress parameters, (a) GSH/GSSG ratio and (b) TBARS, in cold-preserved mouse liver. The study group was divided into five groups as follows: nonpreserved fresh liver, as a control (𝑛=3), PBS (𝑛=3), PBS + 100 mM PEP (𝑛=3), PBS + 100 mM glucose (𝑛=3), and PBS + 10 mM NAC (𝑛=3). Seventy-four hours after storage, the liver tissues were homogenized and analyzed. Each bar represents the mean ± SEM. **𝑃<0.01, compared with the PBS group; ^††𝑃<0.01, compared with the nonpreserved group; ^##𝑃<0.01, compared with the PBS + 100 mM PEP group.

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(b)