Comparative Effects of Phosphoenolpyruvate, a Glycolytic Intermediate, as an Organ Preservation Agent with Glucose and N-Acetylcysteine against Organ Damage during Cold Storage of Mouse Liver and Kidney
Comparative effects of PEP, glucose, and NAC on mouse kidney damage during cold preservation. (a) Changes in LDH concentrations in the preservation solutions; PBS + 100 mM PEP , PBS + 100 mM glucose , and PBS + 10 mM NAC . Each bar represents the mean SEM. #, ##, compared with the PBS + 100 mM PEP group. (b) Histological pictures of the kidney 72 h after cold preservation. The liver tissues were fixed with 10% buffered formalin, embedded in paraffin, sectioned, and stained with hematoxylin-eosin. Scale bar μm.
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.