Table of Contents
ISRN Optics
Volume 2013, Article ID 391972, 5 pages
Research Article

Fossilized Teeth as a New Robust and Reproducible Standard for Polarization-Sensitive Optical Coherence Tomography

1Center for Optical Coherence Tomography and Optical Physics, Department of Orthopedic Surgery, Brigham and Women’s Hospital, 75 Francis Street, Boston, MA 02115, USA
2Harvard Medical School, Boston, MA 02115, USA

Received 11 March 2013; Accepted 3 April 2013

Academic Editors: M. D. Hoogerland, V. Matejec, S. Ponomarenko, S. R. Restaino, and Y. Tsuji

Copyright © 2013 Christopher Vercollone et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A clinical need exists for a cheap and efficient standard for polarization sensitive optical coherence tomography (PS-OCT). We utilize prehistoric fossilized teeth from the Megalodon shark and European horse as an unconventional, yet robust standard. Given their easy accessibility and the microstructural consistency conferred by the process of fossilization, they provide a means of calibration to reduce error from sources such as catheter bending and temperature changes. We tested the maximum difference in birefringence values in each tooth and found the fossilized teeth to be fast and repeatable. The results were compared to measurements from bovine meniscus, tendon, and destroyed tendon, which were verified with histology.