The Effect of Weight Loss on Pediatric Nonalcoholic Fatty Liver Disease

Table 1

Demographic, anthropometric, biochemical, and clinical characteristics of subjects.

Parameter	𝑛	Value	Normal range	Abnormal
Age (years)	81	14.1 (11.2–16.2)	N/A
Sex (𝑛 (%) Male)	81	70 (86%)	N/A
Ethnicity (𝑛 (%))	81		N/A
American Indian		1 (1%)
Asian		51 (63%)
Hispanic		10 (12%)
Pacific Islander		6 (7%)
White		13 (16%)
Body Weight (kg)	81	86.5 ± 26.3	N/A
Height (m)	81	1.60 ± 0.14	N/A
BMI (z-score)	81	2.30 ± 0.40	<1.64	80/81 (99%)
Glucose, Fasting (mmol/L)	33	5.4 (4.9–5.8)	<6.1	6/33 (18%)
Cholesterol (mmol/L)	34	4.8 (4.1–5.7)	<4.4	21/34 (62%)
LDL-cholesterol (mmol/L)	30	2.7 (2.4–3.4)	<3.4	8/30 (27%)
HDL-cholesterol (mmol/L)	27	1.1 ± 0.3	M > 1.0; F > 1.3	14/27 (52%)
Triglycerides (mmol/L)	32	1.9 (1.5–2.5)	<1.7	20/32 (63%)
Systolic Blood Pressure (z-score)	59	1.19 (0.72–1.84)	<1.64	22/59 (37%)
Diastolic Blood Pressure (z-score)	59	0.70 ± 1.07	<1.64
Alanine Aminotransferase (U/L)	81	105 (78–153)	N/A

BMI adjusted for age and sex using the 2000 Centers for Disease Control and Prevention growth charts and lambda, mu and sigma method [17].
Systolic and diastolic blood pressures adjusted for age, sex, and height as per the National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents recommendations [18].
Values are presented as number (percent) for categorical variables, mean ± standard deviation for parametric continuous variables and median (interquartile range) for nonparametric continuous variables. Continuous variables were classified as nonparametric based on Shapiro-Wilk test and confirmed by analysis of frequency distribution graphs.
Normal ranges as per Schwimmer et al. (2003) and Graham et al. (2009) [19, 20]. Abnormal values are frequency (percent) of subjects outside the normal range. Hypertension was present if either systolic or diastolic values were above normal [20].