Table of Contents
ISRN Orthopedics
Volume 2013, Article ID 398298, 6 pages
Clinical Study

Treatment for Wear and Osteolysis in Well-Fixed Uncemented TKR

1Department of Bioengineering, Clemson University, Clemson, SC 29634, USA
2Steadman Hawkins Clinic of the Carolinas, Greenville, SC 29615, USA
3Department of Orthopaedics, USCSOM-Greenville, Greenville, SC 29208, USA

Received 30 November 2012; Accepted 2 January 2013

Academic Editors: P. V. Kumar, G. Matthes, and E. L. Steinberg

Copyright © 2013 Leah Nunez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Traditionally, osteolysis around total knee replacements (TKRs) is treated with complete revision. In certain subsets, polyethylene insert exchange and bone grafting may be applicable. This study reports the clinical outcomes for selective bone grafting in patients with osteolysis without complete revision of the TKR. Methods. This retrospective study analyzes 10 TKRs (9 patients, 66.5 ± 6.1 years old) presenting with osteolysis and revised after 8.7 ± 1.9 years of in vivo function. At index TKR, all patients were implanted with uncemented prosthesis and modular polyethylene insert with anteroposterior articular constraint (Ultracongruent, Natural Knee II, Sulzer Medica). The surgical technique for treating the osteolysis included removal of necrotic bone tissue using curettage, filling of the defect with bone graft materials, and polyethylene insert exchange. Results. Patients have not exhibited any further complications associated with osteolysis after 5.1 ± 2.4 years of followup. Routine radiographic exams show total incorporation of the graft material into the previously lytic regions in all patients. Conclusion. In some TKRs with osteolysis and firmly fixed components, the removal of lytic tissue and subsequent defect filling with bone graft materials can be a viable solution. This case series shows complete resolution of osteolysis in all patients with no complications.