Exploiting Identifiability and Intergene Correlation for Improved Detection of Differential Expression
Figure 1
Results for two variations of Case 1 experiments. In both variations, the number of truly differential genes, , and the “signal strength” (amount of up- or downregulation represented by and ) is weak. (a) Results for Subcase 1.1 in which the size of the gene-discovery list, , is small relative to (). The plot shows (left ordinate) and (right ordinate) values over 40 trials. (b) and results, plotted similarly to those of part (a) of the figure, for Subcase 1.2, in which , large relatively to ().
