Table of Contents
ISRN Computational Biology
Volume 2013 (2013), Article ID 417634, 5 pages
http://dx.doi.org/10.1155/2013/417634
Research Article

HomoKinase: A Curated Database of Human Protein Kinases

Data Mining and Text Mining Laboratory, Department of Bioinformatics, Bharathiar University, Coimbatore, Tamil Nadu 641 046, India

Received 4 March 2013; Accepted 27 March 2013

Academic Editors: G. Colonna and F. Fanelli

Copyright © 2013 Suresh Subramani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

HomoKinase database is a comprehensive collection of curated human protein kinases and their relevant biological information. The entries in the database are curated by three criteria: HGNC approval, gene ontology-based biological process (protein phosphorylation), and molecular function (ATP binding and kinase activity). For a given query protein kinase name, the database provides its official symbol, full name, other known aliases, amino acid sequences, functional domain, gene ontology, pathways assignments, and drug compounds. In addition, as a search tool, it enables the retrieval of similar protein kinases with specific family, subfamily, group, and domain combinations and tabulates the information. The present version contains 498 curated human protein kinases and links to other popular databases.