Multiple Congenital Anomalies after Assisted Reproductive Technology in Japan (between 2004 and 2009)
Table 1
Distribution of classification of cases with congenital anomalies using the EUROCAT computer algorithm.
Number of diseases before algorithm application
Classification after algorithm
Final classification
EUROCAT registries
%
%
Isolated
912
Chromosomal cases
203
15.3%
2,653
15.0%
One
1,115
Chromosomal cases
167
Syndromes
45
3.4%
394
2.2%
Syndromes
36
Isolated
980
74.0%
13,381
75.5%
MCAs
96
7.3%
1,305
7.4%a
Isolated
68
1
24
Neural tube defect isolatedb
5
2
56
Isolated cardiacb
53
Number of ICD subcategories
3
10
More than one
209
Isolated renalb
2
4
5
Isolated otherb
8
5
1
Chromosomal cases
36
Syndromes
9
MCAs
96
Total
1,324
1,324
1,324
17,733
aNumber and % for “true” congenital multiple anomalies.
bThese categories are specifically prepared in the algorithm. EUROAT: European surveillance of congenital anomalies, ICD: International Classification of Disease. MCAs: multiple congenital anomalies.