Improved HPLC Method for the Determination of Moxifloxacin in Application to a Pharmacokinetics Study in Patients with Infectious Diseases

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td align="left">Actual concentration (<i>μ</i>g/mL)</td><td align="center">Peak area ratio</td><td align="center"><span style="width: 33.537498px;"><svg height="12.3625" id="M18" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 33.537498 12.3625" width="33.537498" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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<g transform="matrix(.017,-0,0,-.017,.062,11.925)"><path d="M536 404q0 -17 -13.5 -31.5t-26.5 -14.5q-8 0 -15 10q-11 14 -25 14q-22 0 -67 -50q-47 -52 -68 -82l37 -102q31 -88 55 -88t78 59l16 -23q-32 -48 -68.5 -78t-65.5 -30q-19 0 -37.5 20t-29.5 53l-41 116q-72 -106 -114.5 -147.5t-79.5 -41.5q-21 0 -34.5 14t-13.5 37
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</svg></span></td><td align="center">RSD (%)</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td align="left" rowspan="6">0.5</td><td align="center">1.507</td><td align="center" rowspan="6">1.496 <svg height="9.5625" id="M19" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 10.1 9.5625" width="10.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> 0.020</td><td align="center" rowspan="6">1.31</td></tr><tr><td align="center">1.477</td></tr><tr><td align="center">1.485</td></tr><tr><td align="center">1.496</td></tr><tr><td align="center">1.483</td></tr><tr><td align="center">1.530</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Repeatability (<svg height="11.225" id="M17" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.225" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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t96 -62.5q53 0 78 45.5t25 105.5q0 68 -35 116t-99 48z" id="x36"></path></g>
</svg>).

International Scholarly Research Notices

tab2

Table 2

Table 2: Improved HPLC Method for the Determination of Moxifloxacin in Application to a Pharmacokinetics Study in Patients with Infectious Diseases 