Research Article
Determination of Ranitidine in Human Plasma by SPE and ESI-LC-MS/MS for Use in Bioequivalence Studies
Table 1
Intraday and between-day precision and accuracy for the determination of ranitidine in plasma.
| | Nominal | Concentration (μg/mL) | | Intraday | Between-days | | Determined | RSD (%) | Accuracy | Determined | RSD (%) | Accuracy |
| | 3.00 | 2.79 | 9.75 | 93.2 | 2.92 | 4.04 | 97.3 | | 5.00 | 4.67 | 2.99 | 93.5 | 4.64 | 0.99 | 92.8 | | 200.00 | 197.19 | 3.29 | 98.6 | 202.43 | 2.41 | 101.2 | | 400.00 | 406.26 | 3.37 | 101.6 | 419.38 | 2.73 | 104.8 |
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