Research Article
Impact of Amending the Acetylcysteine Marketing Authorisation on Treatment of Paracetamol Overdose
Table 2
Acetylcysteine administration according to pattern of paracetamol overdose, presented as proportions.
| Overdose pattern | Sept. 2011–Aug. 2012 | Sept. 2012–Apr. 2013 |
| Single time-point ingestion, <15 hours | | | Above “200-line” | 22/22 (100%) | 12/12 (100%) | Between “200-line” and “100-line” | 39/76 (51%) | 44/45 (98%)††† | Below “100-line” | 31/208 (15%) | 22/135 (16%) | Nomogram not applicable | | | Staggered ingestion (>1 hour) | 54/100 (54%) | 47/59 (80%)† | Late presentation (>15 hours) | 12/23 (52%) | 9/13 (69%) | Time of ingestion uncertain | 8/18 (44%) | 7/13 (54%) | Level not checked | 2/36 (6%) | 1/25 (4%) |
| Total | 168/483 (34.8%) | 142/302 (47.0%)†† |
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, ††, ††† versus earlier time period by Chi-square proportional tests.
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