Immunophenotypic Analysis of B Lymphocytes in Patients with Common Variable Immunodeficiency: Identification of CD23 as a Useful Marker in the Definition of the Disease

<table>Possible explanation of B cell maturation defect in patients with CVID. The number of naïve B cells is similar in patients and controls. Since the number of IgM+ IgD− CD23− CD27− B cells is higher and that of IgM− IgD− CD23− CD27− is lower in patients compared to controls, we can hypothesize that the defect in B cell maturation lies at this step of B cell maturation.</table>

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Figure 5: Immunophenotypic Analysis of B Lymphocytes in Patients with Common Variable Immunodeficiency: Identification of CD23 as a Useful Marker in the Definition of the Disease 

Figure 5 | Immunophenotypic Analysis of B Lymphocytes in Patients with Common Variable Immunodeficiency: Identification of CD23 as a Useful Marker in the Definition of the Disease 