Table of Contents
ISRN Nephrology
Volume 2013, Article ID 515292, 4 pages
http://dx.doi.org/10.5402/2013/515292
Clinical Study

Paracetamol Interference in Uric Acid Levels in Uremic Patients Revealed by Monitoring Spent Dialysate

1Department of Biomedical Engineering, Technomedicum, Tallinn University of Technology, Akadeemia tee 5, 19086 Tallinn, Estonia
2National Institute of Chemical Physics and Biophysics, Akadeemia tee 23, 12618 Tallinn, Estonia
3Centre of Nephrology, North-Estonian Medical Centre, J. Sütiste tee 19, 13419 Tallinn, Estonia

Received 21 August 2013; Accepted 11 September 2013

Academic Editors: L. Djukanovic and A. Karel

Copyright © 2013 Risto Tanner et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. Álvarez-Lario and J. Macarrón-vicente, “Is there anything good in uric acid?” QJM, vol. 104, no. 12, Article ID hcr159, pp. 1015–1024, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. T. R. Merriman, “Editorial,” Current Rheumatology Reviews, vol. 7, no. 2, pp. 94–96, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. L. Zhao and G. Pickering, “Paracetamol metabolism and related genetic differences,” Drug Metabolism Reviews, vol. 43, no. 1, pp. 41–52, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. A. Li Wan Po and W. Y. Zhang, “Systematic overview of co-proxamol to assess analgesic effects of addition of dextropropoxyphene to paracetamol,” British Medical Journal, vol. 315, no. 7122, pp. 1565–1571, 1997. View at Google Scholar · View at Scopus
  5. C. Y. Man, I. T. F. Cheung, P. A. Cameron, and T. H. Rainer, “Comparison of oral prednisolone/paracetamol and oral indomethacin/paracetamol combination therapy in the treatment of acute goutlike arthritis: a double-blind, randomized, controlled trial,” Annals of Emergency Medicine, vol. 49, no. 5, pp. 670–677, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. P. Wilding and D. A. Heath, “Effect of paracetamol on uric acid determination,” Annals of Clinical Biochemistry, vol. 12, no. 4, pp. 142–144, 1975. View at Google Scholar · View at Scopus
  7. M. Smith and R. B. Payne, “Re-examination of effect of paracetamol on serum uric acid measured by phosphotungstic acid reduction,” Annals of Clinical Biochemistry, vol. 16, no. 2, pp. 96–99, 1979. View at Google Scholar · View at Scopus
  8. M. Luman, J. Jerotskaja, K. Lauri, and I. Fridolin, “Dialysis dose and nutrition assessment by optical on-line dialysis adequacy monitor,” Clinical Nephrology, vol. 72, no. 4, pp. 303–311, 2009. View at Google Scholar · View at Scopus
  9. A. Castellarnau, M. Werner, R. Günthner, and M. Jakob, “Real-time Kt/V determination by ultraviolet absorbance in spent dialysate: technique validation,” Kidney International, vol. 78, no. 9, pp. 920–925, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. K. Lauri, J. Arund, J. Holmar, R. Tanner, M. Luman, and I. Fridolin, “Optical dialysis adequacy monitoring: small uremic toxins and contribution to UV-absorbance studied by HPLC,” in Progress in Hemodialysis—From Emergent Biotechnology to Clinical Practice, A. Carpi, C. Donadio, and G. Tramonti, Eds., pp. 143–160, InTech, 2011. View at Google Scholar
  11. J. Jerotskaja, F. Uhlin, I. Fridolin, K. Lauri, M. Luman, and A. Fernström, “Optical online monitoring of uric acid removal during dialysis,” Blood Purification, vol. 29, no. 1, pp. 69–74, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. J. Arund, R. Tanner, F. Uhlin, and I. Fridolin, “Do only small uremic toxins—chromophores contribute to the online dialysis dose monitoring by UV absorbance,” Toxins, vol. 4, no. 10, pp. 849–861, 2012. View at Google Scholar
  13. K. Lauri, R. Tanner, J. Jerotskaja, M. Luman, and I. Fridolin, “HPLC study of uremic fluids related to optical dialysis adequacy monitoring,” International Journal of Artificial Organs, vol. 33, no. 2, pp. 96–104, 2010. View at Google Scholar · View at Scopus
  14. A. K. Hewavitharana, S. Lee, P. A. Dawson, D. Markovich, and P. N. Shaw, “Development of an HPLC-MS/MS method for the selective determination of paracetamol metabolites in mouse urine,” Analytical Biochemistry, vol. 374, no. 1, pp. 106–111, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. R. J. Johnson, P. Andrews, S. A. Benner, and W. Oliver, “Theodore E. Woodward award. The evolution of obesity: insights from the mid-Miocene,” Transactions of the American Clinical and Climatological Association, vol. 121, pp. 295–308, 2010. View at Google Scholar · View at Scopus
  16. M. Koelsch, R. Mallak, G. G. Graham et al., “Acetaminophen (paracetamol) inhibits myeloperoxidase-catalyzed oxidant production and biological damage at therapeutically achievable concentrations,” Biochemical Pharmacology, vol. 79, no. 8, pp. 1156–1164, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. D. G. Wickens, A. G. Norden, J. Lunec, and T. L. Dormandy, “Fluorescence changes in human gamma-globulin induced by free-radical activity,” Biochimica et Biophysica Acta, vol. 742, no. 3, pp. 607–616, 1983. View at Google Scholar · View at Scopus
  18. Y. Y. Sautin, T. Nakagawa, S. Zharikov, and R. J. Johnson, “Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress,” American Journal of Physiology, vol. 293, no. 2, pp. C584–C596, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. R. Mohandas and R. J. Johnson, “Uric acid levels increase risk for new-onset kidney disease,” Journal of the American Society of Nephrology, vol. 19, no. 12, pp. 2251–2253, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. R. P. Obermayr, C. Temml, G. Gutjahr, M. Knechtelsdorfer, R. Oberbauer, and R. Klauser-Braun, “Elevated uric acid increases the risk for kidney disease,” Journal of the American Society of Nephrology, vol. 19, no. 12, pp. 2407–2413, 2008. View at Publisher · View at Google Scholar · View at Scopus
  21. F. C. Meotti, G. N. L. Jameson, R. Turner et al., “Urate as a physiological substrate for myeloperoxidase: implications for hyperuricemia and inflammation,” The Journal of Biological Chemistry, vol. 286, no. 15, pp. 12901–12911, 2011. View at Publisher · View at Google Scholar · View at Scopus