Paracetamol Interference in Uric Acid Levels in Uremic Patients Revealed by Monitoring Spent Dialysate

Table 1

Removal ratio (RR) of uric acid (UA) depending on taking of paracetamol (PAR) in the course of dialysis session by patients with end stage kidney disease.

Patient no.	Dosage of PAR		UA in dialysate		Patient
	mg	Last dosage time*	mg/L in start sample	RR %	Sex	Age
No. 1	1000	−90**	22.19	66	F	65
No. 2	500	+95	18.11	43	M	47
No. 3	1000	+30	26.73	47	F	78
No. 4	1000	+45	7.93	47	F	76
No. 5	1000	+10	15.32	49	M	76
No. 6	500	+30	12.61	60	F	47
		Mean ± SD	17.15±6.74	52±9
No. 7	1000	−630***	16.96	77	F	70
Control group	No PAR	Mean ± SD	8.87±2.11	78±14	8 M, 2 F, mean age 62.6±18.6, 10 dialysis sessions in total

Notes: *Time in minutes before (−) of after (+) the start of dialysis.
∗∗Intravenous dropping 10 mg/min, 1 g total beginning from 90 min before dialysis.
∗∗∗The last dosage overnight before the dialysis.