Magnetoencephalography: Fundamentals and Established and Emerging Clinical Applications in Radiology

Table 1

Comparison of distributed source algorithms often used in clinical MEG research.

Name	𝑝	𝑊model	Comment
MNE	2	1	+ simple; − currents packed towards surface of volume
MNE (weighted)	2	1/current-gain	+ no surface bias; − blurry images
LORETA	2	Laplacian^+	+ deep source accurate; − estimates superficial sources too deep
MCE	1	1/current-gain	+ focal estimates; − strong sensitivity to noise

MNE: minimum norm estimate (e.g., [42]). MCE: minimum current estimate [46]. LORETA: low resolution brain electromagnetic tomography [45]. +Mathematical operator representing flux density and gradient flow of a function.