Dietary Supplementation of Calendula officinalis Counteracts the Oxidative Stress and Liver Damage Resulted from Aflatoxin

Table 3

Effect of ethanol extract of calendula on liver antioxidants and lipid peroxidation in rats fed aflatoxins-contaminated diet.

Parameter	Group
	Control	AFs	CE1	CE2	CE1 + AFs	CE2 + AFs
SOD (U/mg liver protein)	299.37 ± 10.33^a	172.32 ± 7.11^b	305.49 ± 21.67^a	310.21 ± 8.32^a	281.57 ± 15.04^c	285.32 ± 9.32^a
GPx (U/mg liver protein)	33.66 ± 2.54^a	14.61 ± 1.20^b	54.03 ± 1.45^c	56.49 ± 2.12^a	35.61 ± 1.43^a	37.43 ± 1.56^a
MDA (nmol/mg liver protein)	37.32 ± 2.12^a	84.31 ± 2.44^b	22.71 ± 2.28^c	20.31 ± 1.44^a	45.26 ± 1.29^d	42.32 ± 2.13^a

Within each row, means superscript with different letters are significantly different at 𝑃 ≤ 0.05.
AFs: aflatoxins.
CE1: low dose of calendula extract (500 mg/kg b.w).
CE2: high dose of calendula extract (1000 mg/kg b.w).