Changes in the Bispectral Index in Response to Experimental Noxious Stimuli in Adults under General Anesthesia

Figure 1

Experimental noxious stimuli (𝑋₁  and  𝑋₂). 𝐵₁: baseline 1; 𝐵₂: baseline 2; 𝑋₁: moderate noxious stimuli (40/100); 𝑋₂: severe noxious stimuli (70/100). Each observation period was 30 seconds in duration. BIS was continuously monitored, and values were documented at 10 second intervals (3 values for each 30 seconds observation period). The maximum BIS value for each 30 second observation period was used for analysis.