Changes in the Bispectral Index in Response to Experimental Noxious Stimuli in Adults under General Anesthesia

Table 2

Relationship between BIS and experimental noxious stimui.

	Median	IQR	Wilcoxon signed-rank test
Moderate experimental noxious stimuli (𝑋1)
𝐵1	35.00	25.75–42.56	𝑃=0.003
𝑋1	40.00	28.50–46.00
Severe experimental noxious stimuli (𝑋2)
𝐵2	37.67	26.75–43.54	𝑃=0.007
𝑋2	40.00	28.00–48.25

Changes in BIS in response to moderate (𝑋₁) and severe (𝑋₂) experimental noxious stimuli. Median and interquartile ranges are indicated for the 4 observation periods (𝐵₁, 𝐵₂, 𝑋₁, and 𝑋₂). For the statistical difference between the two groups of participants, the Wilcoxon signed-rank test was used with 𝑃 values.