Changes in the Bispectral Index in Response to Experimental Noxious Stimuli in Adults under General Anesthesia

Table 5

Changes in BIS in relation to baseline BIS value (≥40 OU <40).

	Median	IQR	Mann-Whitney 𝑈 Test
BIS during moderate noxious stimuli (𝑋1)
𝐵1 < 40 (𝑛=18)	30.50	26.00–40.00	𝑃=0.00
𝐵2 ≥ 40 (𝑛=12)	46.50	43.25–49.50
BIS during severe noxious stimuli (𝑋2)
𝐵1 < 40 (𝑛=18)	30.50	24.75–39.00	𝑃=0.00
𝐵2 ≥ 40 (𝑛=12)	48.50	46.00–53.25

Changes in BIS during moderate and severe noxious stimuli according to whether baseline BIS was ≥40 or <40 were determined. Median and IQR of BIS during both noxious stimuli are noted for each of the two groups. Statistical difference (𝑃 value) between both groups was then calculated for each of the noxious stimuli with the Mann-Whitney 𝑈 Test.
𝐵₁: baseline 1; 𝐵₂: baseline 2; >: superior; <: inferior; IQR: interquartile range; 𝑛: number of participants in each group.