Competitive HIF Prolyl Hydroxylase Inhibitors Show Protection against Oxidative Stress by a Mechanism Partially Dependent on Glycolysis

<table>HIF-1<i>α</i> stabilization and nuclear translocation in differentiated SHSH-5Y cells. The cells were treated with 10 or 25 <i>μ</i>M FG41 for 3 hours, then fixed, and Hoechst-stained. The upper panel shows HIF-1<i>α</i> immunoreactivity alone and the lower panel shows the images merged with the Hoechst-staining.</table>

International Scholarly Research Notices

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Figure 3

Figure 3: Competitive HIF Prolyl Hydroxylase Inhibitors Show Protection against Oxidative Stress by a Mechanism Partially Dependent on Glycolysis 