Research Article

Competitive HIF Prolyl Hydroxylase Inhibitors Show Protection against Oxidative Stress by a Mechanism Partially Dependent on Glycolysis

Table 1

Overview of HPH inhibitors used: chemical structures and HPH specificity.

CompoundIC50 (HPH2)
nM ± SEM
Structure

FG-004148.000 ± 4800598587.tab.001a
DFO30.000 ± 5500598587.tab.001b
CpdA7,0 ± 0,5598587.tab.001c
JNJ-42041935117 ± 8 598587.tab.001d