Design and Characterization of Double Layered Mucoadhesive System Containing Bisphosphonate Derivative

Table 3

Bioadhesive parameters of the mucoadhesive films.

Batch code	Ex vivo mucoadhesive strength (g) mean ± S.D	Force of adhesion (N) mean ± S.D	Bond strength (Nm^−2) mean ± S.D	Mucoadhesion time (h) mean ± S.D
A1	30.67±12.89	0.301±0.127	13.37±5.62	8.29±0.52
A2	26.33±2.31	0.258±0.023	11.48±1.00	8.36±0.56
A3	27.67±2.08	0.271±0.020	12.06±0.91	7.50±0.66
A4	35.67±12.90	0.350±0.127	15.55±5.62	12.13±0.84
A5	35.01±3.23	0.343±0.130	15.26±5.76	7.33±1.23
A6	29.33±1.16	0.288±0.011	12.78±0.50	10.44±0.29
A7	37.67±4.79	0.370±0.106	16.42±4.70	9.22±1.23
A8	31.67±7.64	0.311±0.076	13.80±3.33	8.44±0.9
A9	42.33±6.62	0.415±0.163	18.45±7.24	7.13±1.75
A10	34.13±4.15	0.334±0.100	14.823±4.42	7.39±1.26
A11	39.26±5.53	0.350±0.141	15.55±6.26	11.50±0.98
A12	28.33±1.53	0.278±0.015	12.35±0.66	10.44±0.46
A13	46.67±2.82	0.458±0.204	20.347±9.07	12.32±0.21
A14	26.94±3.61	0.255±0.035	11.33±1.57	8.11±0.89