Conservation of the Nuclear Receptor Response Element in HIV-1 LTRs: A Possible PPAR Response Element?
Figure 3
The NRRE-1-DE sequence is highly conserved in HIV-1 isolates from USA. (a) The alignment of the 5′-LTR sequences from the beginning of the sequence provided, with identical nucleotides in black and similar nucleotides in grey. The position of the NRRE-1-DE is indicated above the sequences. (b) Sequence logo of the NRRE-1-DE in the 5′-LTRs of HIV-1 from USA isolates, showing conservation of nucleotides throughout the motif with degeneracy at positions 150 and 153. The colour scheme is as indicated in the legend for Figure 2. The GenBank accession numbers for the source sequences are AY376247.1–AY376266.1.
