Conservation of the Nuclear Receptor Response Element in HIV-1 LTRs: A Possible PPAR Response Element?

Table 1

The functional PPRE sequences from several cellular metabolism genes, showing the variability in the half-sites and spacer nucleotides. The half-site sequences are shown in uppercase letters, while the spacer nucleotide is written in lowercase ones.

Gene name	Species	PPRE (5′ to 3′)	Reference
HMG-CoAS	Not indicated	AGACCTtTGGCCC	[15]
Lipoprotein lipase	Not indicated	TGCCCTtTCCCCC	[15]
Acyl-CoA oxidase	Rat	TGACCTtTGTCCT	[16]
Acyl CoA oxidase (active)	Human	AGGTCAcTGGTCA	[17]
Acyl CoA oxidase (inactive)	Human	AGGTCAgCTGTCA	[17]
Peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase (HD)	Rat	TGACCTaTGACCT	[18]
Malic enzyme—proximal site	Not indicated	GGGTCAaAGTTGA	[19]
Adipose differentiation-related protein	Human	AGGTGAaAGGGCG	[20]
Pancreatic-duodenal-homeobox-(PDX-) 1	Mouse	GGGTACcTCCAGT	[21]
Pancreatic-duodenal-homeobox-(PDX-) 1	Human	AAGGACcTCCAGT	[21]