Table of Contents
ISRN Toxicology
Volume 2013, Article ID 610648, 6 pages
Research Article

Potential Toxic Levels of Cyanide in Almonds (Prunus amygdalus), Apricot Kernels (Prunus armeniaca), and Almond Syrup

1Laboratoire De Toxicologie, Centre D’assistance Medicale et Urgente, Tunis, Tunisia
2Unité de Recherche du Laboratoire de Toxicologie et Environnement LR12SP07, 10 rue Aboul Kacem Chabbi, 1008 Montfleury, Tunis, Tunisia

Received 16 July 2013; Accepted 25 August 2013

Academic Editors: J. Llorens, P. Urban, and S. M. Waliszewski

Copyright © 2013 Nadia Chaouali et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. J. Ballhom, “Cyanogenic glycosides in nuts and seeds,” in Nuts & Seeds in Health and Disease Prevention, V. R. Preedy, R. R. Watson, and V. B. Patel, Eds., pp. 129–136, Academic Press is an imprint of Elsevier, London, UK, 1st edition, 2011. View at Google Scholar
  2. D. S. Seigler, “Isolation and characterization of naturally occurring cyanogenic compounds,” Phytochemistry, vol. 14, no. 1, pp. 9–29, 1975. View at Google Scholar · View at Scopus
  3. M. R. Haque and J. H. Bradbury, “Total cyanide determination of plants and foods using the picrate and acid hydrolysis methods,” Food Chemistry, vol. 77, no. 1, pp. 107–114, 2002. View at Publisher · View at Google Scholar · View at Scopus
  4. G. Drochioiu, C. Arsene, M. Murariu, and C. Oniscu, “Analysis of cyanogens with resorcinol and picrate,” Food and Chemical Toxicology, vol. 46, no. 11, pp. 3540–3545, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. A. E. Burns, J. H. Bradbury, T. R. Cavagnaro, and R. M. Gleadow, “Total cyanide content of cassava food products in Australia,” Journal of Food Composition and Analysis, vol. 25, no. 1, pp. 79–82, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. International standard ISO, Pulses-Determination of Glycosidic Hydrocyanic Acid, 1st edition, 1975.
  7. J. Hamel, “A review of acute cyanide poisoning with a treatment update,” Critical Care Nurse, vol. 31, no. 1, pp. 72–82, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. A. H. Hall, R. Dart, and G. Bogdan, “Sodium thiosulfate or hydroxocobalamin for the empiric treatment of cyanide poisoning?” Annals of Emergency Medicine, vol. 49, no. 6, pp. 806–813, 2007. View at Publisher · View at Google Scholar · View at Scopus
  9. L. Coentrão and D. Moura, “Acute cyanide poisoning among jewelry and textile industry workers,” American Journal of Emergency Medicine, vol. 29, no. 1, pp. 78–81, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. F. Dicenta, P. Martínez-Gómez, N. Grané et al., “Relationship between cyanogenic compounds in kernels, leaves, and roots of sweet and bitter kernelled almonds,” Journal of Agricultural and Food Chemistry, vol. 50, no. 7, pp. 2149–2152, 2002. View at Publisher · View at Google Scholar · View at Scopus
  11. WHO, “Cyanogenic glycosides (Who Food Additives Series 30),”, 2012.
  12. Committee on toxicity of chemicals in food, consumer products and the environment, “Statement on cyanogenic glycosides in bitter apricot kernels,”
  13. J. C. Blain and M. Grisvard, Plantes Vénéneuses, la maison Rustique, Paris, France, 1973.
  14. M. Frehner, M. Scalet, and E. E. Conn, “Pattern of the cyanide-potential in developing fruits: Implications for plants accumulating cyanogenic monoglucosides (Phaseolus lunatus) or cyanogenic diglucosides in their seeds (Linum usitatissimum, Prunus amygdalus),” Plant Physiology, vol. 94, no. 1, pp. 28–34, 1990. View at Google Scholar · View at Scopus
  15. R. Arbouche, F. Arbouche, H. S. Arbouche, and Y. Arbouche, “Valeur nutritive d'un oléagineux dans l'alimentation des ruminants: cas de l'amande d'abricot et de son tourteau,” Livestock Research for Rural Development; 19, Article 189, 2007,
  16. G. M. O'Brien, L. Mbome, A. J. Taylor, and N. H. Poulter, “Variations in cyanogen content of cassava during village processing in Cameroon,” Food Chemistry, vol. 44, no. 2, pp. 131–136, 1992. View at Publisher · View at Google Scholar · View at Scopus
  17. Santé Canada, “Le cyanure,”, 2013.
  18. R. K. Chadha, J. F. Lawrence, and W. M. N. Ratnayake, “Ion chromatographic determination of cyanide released from flaxseed under autohydrolysis conditions,” Food Additives and Contaminants, vol. 12, no. 4, pp. 527–533, 1995. View at Google Scholar · View at Scopus
  19. S. C. Cunnane, S. Ganguli, C. Menard et al., “High α-linolenic acid flaxseed (Linum usitatissimum): some nutritional properties in humans,” British Journal of Nutrition, vol. 69, no. 2, pp. 443–453, 1993. View at Google Scholar · View at Scopus
  20. R. Baumeister, “Toxicological and clinical aspects of cyanide metabolism,” Arzneimittel-Forschung, vol. 25, no. 7, pp. 1056–1064, 1975. View at Google Scholar
  21. J. Davidson, “Cyanide, cassava and diabetes,” The Lancet, vol. 11, pp. 635–636, 1979. View at Google Scholar
  22. H. Wajant, D. Riedel, S. Benz, and K. W. Mundry, “Immunocytological localization of hydroxynitrile lyases from Sorghum bicolor L. and Linum usitatissimum L,” Plant Science, vol. 103, no. 2, pp. 145–154, 1994. View at Google Scholar · View at Scopus
  23. FSANZ, “Final assessment report proposal. Advice on the preparation of cassava and bamboo shoots, Canberra,”, 2004.
  24. EFSA, “Opinion of the scientific panel on food additives, flavouring, processing aids and materials in contact with food (AFC) on hydrocyanic acid in flavouring and other food ingredients with flavouring properties,” EFSA Journal, vol. 105, pp. 1–28, 2004. View at Google Scholar