Downregulation of Caspase-2 Expression in Somitic Cells following Coculture with Chicken Notochord
Figure 4
RT-PCR analysis for somitic cells in somite groups on day 0 and 6 and somite cocultured with notochord (Som + Not) group six days after culturing (a). Semiquantitative analysis clearly showed that expression of Pax1, Bcl2, and BMP4 was upregulated in somitic cells cocultured with notochord but MyoD, Caspase-2, and Pax3 expressions were downregulated compared to the cells in Som (day 0) (*) and Som (day 6) groups (†) (b).