DLK1 Protein Expression during Mouse Development Provides New Insights into Its Function

Figure 6

DLK1 protein expression in the developing lung. ((A)–(D)) They show sections of ED10, -13, -16, and -18 lungs. Positive DLK1 staining on ED10- and -13 is located in the distal growing epithelium of the lung buds (arrows in (A) and (B)), with less intense staining in the surrounding mesenchyme. On ED16, positivity is still confined to the distally located epithelium of the terminal bronchioli (inset in (C); bar: 10 μm). ED18 lung shows only residual positivity in the epithelium of the alveoli (inset in (D); bar: 10 μm). (a) alveolus. Scale bar in (A) is applicable for ((B)–(D)).