Design, Synthesis, and In Vitro Antimicrobial Evaluation of Fused Pyrano[3,2-e]tetrazolo[1,5-c]pyrimidines and Diazepines

Scheme 1

Schematic representation for the synthesis of fused tetrazole derivatives. Reagents and conditions: (i) NaN₃, DMF, NH₄Cl, 120°C, 7 h; (ii) CS₂, pyridine, reflux, 10 h; (iii) conc. HCl, benzaldehyde, MeOH, reflux, 16 h; (iv) 4-methoxyphenacyl bromide, EtOH, AcONa, reflux, 16 h.