Table of Contents
ISRN Endocrinology
Volume 2013, Article ID 641098, 7 pages
http://dx.doi.org/10.1155/2013/641098
Clinical Study

Hypovitaminosis D in Patients with Type 2 Diabetes Mellitus: A Relation to Disease Control and Complications

1Department of Internal Medicine, Division of Endocrinology, American University of Beirut Medical Center, P.O. Box 11-0236, Riad El-Solh, Beirut 1107 2020, Lebanon
2Department of Family Medicine, American University of Beirut Medical Center, P.O. Box 11-0236, Riad El-Solh, Beirut 1107 2020, Lebanon

Received 17 August 2013; Accepted 5 September 2013

Academic Editors: C.-H. Anderwald and N. T. Raymond

Copyright © 2013 Hala Ahmadieh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. Sherwin and A. M. Jastreboff, “Year in diabetes 2012: the diabetes tsunami,” Journal of Clinical Endocrinology & Metabolism, vol. 97, pp. 4293–4301, 2012. View at Google Scholar
  2. A. G. Pittas, J. Lau, F. B. Hu, and B. Dawson-Hughes, “The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis,” Journal of Clinical Endocrinology & Metabolism, vol. 92, no. 6, pp. 2017–2029, 2007. View at Publisher · View at Google Scholar · View at Scopus
  3. R. Raman, A. Gupta, S. Krishna, V. Kulothungan, and T. Sharma, “Prevalence and risk factors for diabetic microvascular complications in newly diagnosed type II diabetes mellitus. Sankara Nethralaya Diabetic Retinopathy Epidemiology And Molecular Genetic Study (SN-DREAMS, report 27),” Journal of Diabetes and Its Complications, vol. 26, pp. 123–128, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. A. Girach, D. Manner, and M. Porta, “Diabetic microvascular complications: can patients at risk be identified? A review,” International Journal of Clinical Practice, vol. 60, no. 11, pp. 1471–1483, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. M. Mata-Cases, C. De Prado-Lacueva, V. Salido-Valencia et al., “Incidence of complications and mortality in a type 2 diabetes patient cohort study followed up from diagnosis in a primary healthcare centre,” International Journal of Clinical Practice, vol. 65, pp. 299–307, 2011. View at Google Scholar
  6. C. R. L. Cardoso and G. F. Salles, “Predictors of development and progression of microvascular complications in a cohort of Brazilian type 2 diabetic patients,” Journal of Diabetes and Its Complications, vol. 22, no. 3, pp. 164–170, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. P. Lips, “Vitamin D status and nutrition in Europe and Asia,” Journal of Steroid Biochemistry and Molecular Biology, vol. 103, no. 3–5, pp. 620–625, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. M.-H. Gannage-Yared, R. Chemali, N. Yaacoub, and G. Halaby, “Hypovitaminosis D in a sunny country: relation to lifestyle and bone markers,” Journal of Bone and Mineral Research, vol. 15, no. 9, pp. 1856–1862, 2000. View at Google Scholar · View at Scopus
  9. S. B. Mohr, “A brief history of vitamin D and cancer prevention,” Annals of Epidemiology, vol. 19, no. 2, pp. 79–83, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. J. M. Lappe, D. Travers-Gustafson, K. M. Davies, R. R. Recker, and R. P. Heaney, “Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial,” The American Journal of Clinical Nutrition, vol. 85, pp. 1586–1591, 2007. View at Google Scholar
  11. R. Staud, “Vitamin D: more than just affecting calcium and bone,” Current Rheumatology Reports, vol. 7, no. 5, pp. 356–364, 2005. View at Google Scholar · View at Scopus
  12. S. Nagpal, S. Na, and R. Rathnachalam, “Noncalcemic actions of vitamin D receptor ligands,” Endocrine Reviews, vol. 26, no. 5, pp. 662–687, 2005. View at Publisher · View at Google Scholar · View at Scopus
  13. W. Janssens, A. Lehouck, C. Carremans, R. Bouillon, C. Mathieu, and M. Decramer, “Vitamin d beyond bones in chronic obstructive pulmonary disease; time to act,” American Journal of Respiratory and Critical Care Medicine, vol. 179, no. 8, pp. 630–636, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. K. B. Gibney, L. MacGregor, K. Leder et al., “Vitamin D deficiency is associated with tuberculosis and latent tuberculosis infection in immigrants from sub-Saharan Africa,” Clinical Infectious Diseases, vol. 46, no. 3, pp. 443–446, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. G. Karatekin, A. Kaya, O. Salihoglu, H. Balci, and A. Nuhoglu, “Association of subclinical vitamin D deficiency in newborns with acute lower respiratory infection and their mothers,” European Journal of Clinical Nutrition, vol. 63, pp. 473–477, 2007. View at Google Scholar
  16. J. Kendrick, G. Targher, G. Smits, and M. Chonchol, “25-Hydroxyvitamin D deficiency is independently associated with cardiovascular disease in the Third National Health and Nutrition Examination Survey,” Atherosclerosis, vol. 205, no. 1, pp. 255–260, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. M. T. Cantorna, “Vitamin D and multiple sclerosis: an update,” Nutrition Reviews, vol. 66, supplement 2, pp. S135–S138, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. L. Adorini and G. Penna, “Control of autoimmune diseases by the vitamin D endocrine system,” Nature Clinical Practice Rheumatology, vol. 4, no. 8, pp. 404–412, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. G. Isaia, R. Giorgino, and S. Adami, “High prevalence of hypovitaminosis D in female type 2 diabetic population,” Diabetes Care, vol. 24, no. 8, p. 1496, 2001. View at Google Scholar · View at Scopus
  20. A. G. Need, P. D. O'Loughlin, M. Horowitz, and B. E. C. Nordin, “Relationship between fasting serum glucose, age, body mass index and serum 25 hydroxyvitamin D in postmenopausal women,” Clinical Endocrinology, vol. 62, no. 6, pp. 738–741, 2005. View at Publisher · View at Google Scholar · View at Scopus
  21. R. Scragg, M. Sowers, and C. Bell, “Serum 25-hydroxyvitamin D, diabetes, and ethnicity in the Third National Health and Nutrition Examination Survey,” Diabetes Care, vol. 27, no. 12, pp. 2813–2818, 2004. View at Publisher · View at Google Scholar · View at Scopus
  22. R. Scragg, “Vitamin D and type 2 diabetes: are we ready for a prevention trial?” Diabetes, vol. 57, no. 10, pp. 2565–2566, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. L. Danescu, S. Levy, and J. Levy, “Vitamin D and diabetes mellitus,” Endocrine, vol. 35, pp. 11–17, 2008. View at Google Scholar
  24. C. Mattila, P. Knekt, S. Männistö et al., “Serum 25-hydroxyvitamin D concentration and subsequent risk of type 2 diabetes,” Diabetes Care, vol. 30, no. 10, pp. 2569–2570, 2007. View at Publisher · View at Google Scholar · View at Scopus
  25. C. Dalgård, M. S. Petersen, P. Weihe, and P. Grandjean, “Vitamin D status in relation to glucose metabolism and type 2 diabetes in septuagenarians,” Diabetes Care, vol. 34, no. 6, pp. 1284–1288, 2011. View at Publisher · View at Google Scholar · View at Scopus
  26. P. Pietschmann, G. Schernthaner, and W. Woloszczuk, “Serum osteocalcin levels in diabetes mellitus: analysis of the type of diabetes and microvascular complications,” Diabetologia, vol. 31, no. 12, pp. 892–895, 1988. View at Google Scholar · View at Scopus
  27. A. Suzuki, M. Kotake, Y. Ono et al., “Hypovitaminosis D in type 2 diabetes mellitus: association with microvascular complications and type of treatment,” Endocrine Journal, vol. 53, no. 4, pp. 503–510, 2006. View at Publisher · View at Google Scholar · View at Scopus
  28. T. Inukai, Y. Fujiwara, K. Tayama, Y. Aso, and Y. Takemura, “Alterations in serum levels of 1α,25(OH)2 D3 and osteocalcin in patients with early diabetic nephropathy,” Diabetes Research and Clinical Practice, vol. 38, no. 1, pp. 53–59, 1997. View at Publisher · View at Google Scholar · View at Scopus
  29. P. Naveilhan, I. Neveu, D. Wion, and P. Brachet, “1,25-Dihydroxyvitamin D3, an inducer of glial cell line-derived neurotrophic factor,” NeuroReport, vol. 7, no. 13, pp. 2171–2175, 1996. View at Google Scholar · View at Scopus
  30. P. Lee and R. Chen, “Vitamin D as an analgesic for patients with type 2 diabetes and neuropathic pain,” Archives of Internal Medicine, vol. 168, no. 7, pp. 771–772, 2008. View at Publisher · View at Google Scholar · View at Scopus
  31. M. J. Young, A. J. M. Boulton, A. F. Macleod, D. R. R. Williams, and P. H. Sonksen, “A multicentre study of the prevalence of diabetic peripheral neuropathy in the United Kingdom hospital clinic population,” Diabetologia, vol. 36, no. 2, pp. 150–154, 1993. View at Publisher · View at Google Scholar · View at Scopus
  32. M. S. Hutchinson, Y. Figenschau, I. Njølstad, H. Schirmer, and R. Jorde, “Serum 25-hydroxyvitamin D levels are inversely associated with glycated haemoglobin (HbA1c). The Tromsø Study,” Scandinavian Journal of Clinical and Laboratory Investigation, vol. 71, no. 5, pp. 399–406, 2011. View at Publisher · View at Google Scholar · View at Scopus
  33. L. A. Plum and J. B. Zella, “Vitamin D compounds and diabetic nephropathy,” Archives of Biochemistry and Biophysics, vol. 523, pp. 87–94, 2012. View at Publisher · View at Google Scholar · View at Scopus
  34. P. A. Patrick, P. F. Visintainer, Q. Shi, I. A. Weiss, and D. A. Brand, “Vitamin d and retinopathy in adults with diabetes mellitus,” Archives of Ophthalmology, vol. 1, pp. 756–760, 2012. View at Google Scholar
  35. D. M. Albert, E. A. Scheef, S. Wang et al., “Calcitriol is a potent inhibitor of retinal neovascularization,” Investigative Ophthalmology and Visual Science, vol. 48, no. 5, pp. 2327–2334, 2007. View at Publisher · View at Google Scholar · View at Scopus
  36. K. Bućan, M. Ivanisević, T. Zemunik et al., “Retinopathy and nephropathy in type 1 diabetic patients–association with polymorphysms of vitamin D-receptor, TNF, Neuro-D and IL-1 receptor 1 genes,” Collegium Antropologicum, vol. 33, supplement 2, pp. 99–105, 2009. View at Google Scholar · View at Scopus