Soy Saponins Meditate the Progression of Colon Cancer in Rats by Inhibiting the Activity of β-Glucuronidase and the Number of Aberrant Crypt Foci but Not Cyclooxygenase-2 Activity

Table 4

The distribution of ACFs according to different sections of the colon^1,2.

	The incidence of ACFs^3	Proximal	Middle	Distal	Total
PS0	0/4	ND^4	ND	ND	ND
PS0.5	0/4	ND	ND	ND	ND
DS0	6/6	4.50±0.67^a	7.17±0.62^a	15.50±1.35^a	27.00±1.91^a
DS0.5	6/6	2.00±0.28^ab	4.83±0.33^a	9.83±0.43^b	16.67±0.44^b
DS1	6/6	1.00±0.35^b	1.83±0.50^b	5.17±0.81^b	8.00±1.41^c

1Data are expressed as Mean ± SEM (𝑛=6).
²PS0: received saline and fed AIN93G diet; PS0.5: received saline and fed AIN93G diet containing 0.5% saponins; DS0: received 1,2-dimethylhydrazine (DMH) and fed AIN93G diet; DS0.5: received DMH and fed AIN93G diet containing 0.5% saponins; DS1: received DMH and fed AIN93G diet containing 1% saponins.
³The incidence of ACFs is the number of ACF rats/the number of total rats.
⁴ND: No detection.
^abcLetters in each column sharing the different superscripts are significantly different (𝑃<0.05).