Research Article
Toxic Epidermal Necrolysis and Graft-versus-Host Reaction: Revisiting a Puzzling Similarity
Table 3
Medians (ranges) of cell densities/mm2 in the epidermis and superficial dermis of TEN, acute GVHR, and PTTB.
| | Cells/marker | TEN | GVHR | PTTB |
| | Dermal T lymphocytes | | | | | CD45RO | 8 (2–19) | 13 (9–29) | 5 (1–9) | | CD4 | 4 (0–10) | 9 (5–16) | 2 (0–6) | | CD8 | 2 (0–5) | 3 (0–6) | 1 (0–3) | | Dermal macrophages | | | | | Mac 387 | 17 (9–31) | 19 (13–38) | 6 (1–8) | | CD68 | 6 (3–10) | 9 (5–17) | 1 (0–4) | | Myeloperoxidase | 4 (3–9) | 3 (2–8) | 0 (0–3) | | Lysozyme | 5 (3–8) | 10 (3–16) | 1 (0–5) | | Dermal dendrocytes | | | | | Factor XIIIa | 48 (24–65) | 61 (45–83) | 52 (33–68) | | CD34 | 9 (6–15) | 12 (8–17) | 12 (5–16) | | Versican | 15 (7–32) | 19 (14–42) | 8 (3–17) | | Keratinocytes | | | | | Mac 387 | 389 (206–551) | 296 (157–319) | 29 (20–39) | | UEA-1 | 97 (33–197) | 78 (12–94) | 33 (6–81) | | CD44 var 3 | 408 (396–569) | 333 (315–378) | 15 (12–218) | | GSTπ | 32 (0–95) | 15 (3–61) | 0 (0–4) | | Ki67 | 6 (0–19) | 9 (7–42) | 15 (0–63) | | CK15 | 3 (0–8) | 1 (0–4)
| 4 (0–7) |
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