SUMOhunt: Combining Spatial Staging between Lysine and SUMO with Random Forests to Predict SUMOylation

Table 1

Physicochemical properties used to shape SUMOhunt. They were chosen because of their potential contribution in docking of SUMO with substrate protein at the target site.

Amino acid property	AAIndex	Year reported
Hydrophobicity	PRAM900101	1990
Polarity	GRAR740102	1974
Bulkiness	ZIMJ680102	1968
Hydropathy index	KYTJ820101	1982
Accessible surface area	RADA880106	1988
Residue accessible surface area in tripeptide	CHOC760101	1976
Percentage of buried residues	JANJ780102	1978
Entropy of formation	HUTJ700103	1970
Side-chain volume	KRIW790103	1979
Side-chain’s contribution to stability	TAKK010101	2001
Buriability	ZHOH040103	2004
Hydrophilicity value	HOPT810101	1981
Molecular weight	FASG760101	1976
Transfer free energy to surface	BULH740101	1974
Steric parameter	CHAM810101	1981
Isoelectric point	ZIMJ680104	1968