Clinical Study
Computed Tomography Angiography before Intravenous Thrombolysis Does Not Increase the Risk of Renal Dysfunction
Table 1
Patient characteristics in the CTA group and control group.
| | | Control group | CTA group | P |
| | Age (y), mean (±SD) | 71.5 (10.7) | 65.3 (16.2) | 0.05 | | Male sex, (%) | 63 (54.8) | 29 (61.7) | 0.4 | | History of diabetes, (%) | 28 (24.3) | 11 (23.4) | 0.9 | | History of hypertension, (%) | 70 (60.9) | 30 (63.8) | 0.7 | | History of chronic renal insufficiency, (%) | 8 (7) | 1 (2.1) | 0.2 | | Previous stroke, (%) | 10 (8.7) | 2 (4.3) | 0.3 | | Previous use of metformin, (%) | 20 (17.4) | 8 (17) | 0.9 | | Previous use of nonsteroidal anti-inflammatory drugs, (%) | 15 (13) | 3 (6.4) | 0.2 | | Baseline NIHSS score, median (IQR) | 13 (8–17) | 14 (7–18) | 0.9 | | Baseline creatinine >1.5 mg/dL, (%) | 5 (4.3) | 4 (8.5) | 0.3 | | Baseline glucose levels (in mg/dL), mean (±SD) | 132.3 (43.8) | 136 (57.1) | 0.6 | | Baseline creatinine levels (in mg/dL), mean (±SD) | 0.99 (0.75) | 0.93 (0.33) | 0.5 | | Creatinine levels within 24–72 hours after IVT (in mg/dL), mean (±SD) | 0.96 (0.90) | 0.86 (0.32) | 0.3 | Risk score of CIN
(Mehran et al.) [1], mean (±SD) | NA | 5.6 (4) | NA | | Total contrast dose (mL), mean (±SD) | NA | 105.2 (33.4) | NA |
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CTA: computed tomography angiography; SD: standard deviation; NIHSS: National Institutes of Health Stroke Scale; IQR: interquartile range; IVT: intravenous thrombolysis; CIN: contrast-induced nephropathy; NA: not applicable.
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