Clinical Study
Computed Tomography Angiography before Intravenous Thrombolysis Does Not Increase the Risk of Renal Dysfunction
Table 4
Univariate and multivariate linear regression analyses to predict creatinine increase in 24–72 hours compared with baseline.
| | Univariate analysis | Multivariate analysis | | Standardised coefficient | P | Standardised coefficient | P |
| Age | | 0.22 | | | Male sex | 0.081 | 0.30 | | | History of diabetes | 0.071 | 0.37 | | | History of hypertension | 0.02 | 0.78 | | | History of chronic renal insufficiency | 0.41 | <0.001 | 0.20 | 0.01 | Previous stroke | 0.05 | 0.56 | | | Use of metformin | | 0.64 | | | Baseline glucose levels | | 0.62 | | | Baseline NIHSS score | | 0.25 | | | Baseline creatinine | 0.46 | <0.001 | 0.30 | <0.001 | Baseline systolic blood pressure | | 0.78 | | | Use of nonsteroidal anti-inflammatory drugs | 0.29 | <0.001 | 0.19 | 0.008 | CTA performance | | 0.31 | | | Risk score of CIN (Mehran et al.) [1] | | 0.24 | | | Contrast dose | | 0.19 | | |
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NIHSS: National Institutes of Health Stroke Scale; CTA: computed tomography angiography; CIN: contrast-induced nephropathy.
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