Research Article

Three Component Reaction: An Efficient Synthesis and Reactions of 3,4-Dihydropyrimidin-2(1H)-Ones and Thiones Using New Natural Catalyst

Table 2

3,4-Dihydropyrimidin-2(1H)-thiones (IV).

EntryR1R2R3Time (h)MP. [Reference]Yielda
QuartzGraniteFoundReportedQuartzGranite

IVaC6H5OEtPh33183-184183–185 [45]6360
IVb4-(OCH3)-C6H4CH3CH33.54181-182183-184 [46]6765
IVc2,3-(OCH3)-C6H3OEtCH33.54181–183New6463
IVd4-(OCH3)-C6H4OEtCH334152-153150–152 [43]5956
IVe2-(OH)-C6H4 OEtCH334 210-211206–208 [47]6359
IVf2,6-(Cl)-C6H3OEtCH345222–224New5560
IVg3-(OCH2Ph)-C6H4OEtCH334180–182New6660
IVh2,5-(OCH3)-C6H3OEtCH34.55188–190New6460

Isolated yield.