A C-Terminal Transmembrane Anchor Targets the Nuage-Localized Spermatogenic Protein Gasz to the Mitochondrial Surface

<table>Model for Gasz tethering of the nuage to the mitochondrial outer membrane. MitoPLD is a homodimer that inserts via an N-terminal transmembrane anchor into the mitochondrial outer membrane. MILI, TDRD1, and RanBP9 localize to the nuage and MVH to the periphery of the nuage at the boundary with the mitochondria. Gasz is proposed, via its physical interactions with MVH, MILI, TDRD1, and RanBP9 and its anchored insertion into the mitochondrial outer membrane, to help juxtapose the nuage to the mitochondrial surface. </table>

International Scholarly Research Notices

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Figure 5

Figure 5: A C-Terminal Transmembrane Anchor Targets the Nuage-Localized Spermatogenic Protein Gasz to the Mitochondrial Surface 